The new formation came after Yan's former partner, Zheng Jie, withdrew from the Grand Slam tournament because of injury, according to website Sina.com.
The other Chinese duo in the event is Sun Shengnan and Ji Chunmei, while remaining compatriots, Sun Tiantian, Li Na and Yuan Meng, will join foreign players to compete.
Yan Zi and Zheng Jie became the first Chinese crowned Grand Slams last year after pocketing both womens doubles titles in the Australian Open and Wimbledon Open.
This year's Wimbledon Open will kick off on June 25.
